Jonathan Taylor

Jonathan Taylor (ankle) did not practice Wednesday.

Taylor suffered a high-ankle sprain in the Colts’ Week 4 win over the Steelers. His absence from practice isn’t a surprise and he is likely to miss multiple weeks with the ankle injury. Trey Sermon is the next man up for Indy. He should get the bulk of the carries with Tyler Goodson pitching in on passing downs. Sermon should be added in all formats and will rank as a high-risk RB3 once Taylor is ruled out.