Josh Downs

Josh Downs (ankle) was limited at practice Wednesday.

The Colts have long targeted a Week 2 return for Downs, who suffered a high ankle sprain last month during training camp. It’s possible Downs could see limited usage in his return to the Colts lineup. With Downs sidelined in Week 1 against the Texans, Adonai Mitchell and Alec Pierce joined Michael Pittman in three-receiver sets. Pierce had two long connections with Anthony Richardson while Mitchell turned 85 air yards into two actual yards.